January 22, 2020

Two new grad students joined the Shin laboratory this year. Jihye Han and Huiwon Cho joined the laboratory to pursue their Ph.D. in stem cell / cancer research. We are excited to have them in lab, and WELCOME!!!

January 21, 2020

Congratulations, Eunjee! 

Eunjee Kim received the Best Poster Presentation Award at the 2020 Korean Society for Molecular and Cellular Biology conference held in January. Eunjee is the third year Ph.D student and her research focuses on the development of next generation organoid technology including assembloids.

May 28, 2019

In order to grow, cancer cells shut down or over-activate genes that normally maintain a cell’s health. The Sonic Hedgehog gene – named after a Japanese cartoon character – is associated with the cancer of several tissues, including the bladder. In 2014, our team found that losing the Sonic Hedgehog gene (Shh) is necessary for bladder cancers to become aggressive: Shh signals prompt healthy cells near the tumor to inhibit the cancer cell growth, w...

April 18, 2019

Congratulations, Seoyoung! 

Seoyoung Choi, the first year graduate student, received the KEF Award from Kwangjeong Educational Foundation. This scholarship is awarded to the outstanding graduate students who have great potential to excel their fields. Seoyoung plans to use this scholarship to pursue her research on the development of better organoid model platform to study various neurological diseases including schizophrenia. 

September 14, 2018

Congratulations, Eunjee! 

Eunjee Kim received the Best Poster Award at the 2018 Korean Society for Stem Cell Research conference held in August. Eunjee is the first year Ph.D student and her research focuses on the stem cell regulation in various epithelial tissues including bladder and brain.

August 1, 2018

New postdoctoral fellow joined the Shin laboratory this summer! Dr. Jeongwoo Kwon received his Ph.D. at Chungbuk National University, and was recently awarded a Research Fellowship from National Research Foundation of Korea. His research focuses on brain organoids which will be utilized for better understanding of neurological diseases such as schizophrenia and autisms.

October 1, 2017

Sung Eun Kim received the Best Poster Presentation Award at the 2017 International Conference of the Korean Society for Molecular and Cellular Biology held in September. Sung Eun is the first year Ph.D student. Her research focuses on the epigenetic regulation of Hedgehog signaling and its effect on the development of aggressive subtype of bladder cancer called basal urothelial carcinoma which is associated with poor patient survival....

March 13, 2017

In our study, published Mar 9 in Science, we found the novel role of Gli2, the major Hedgehog pathway transcription effectors, on the regulation of a niche signaling program for mammary epithelial stem cells. The mammary gland niche support its associated stem cells while also responding to systemic hormonal regulation that triggers pubertal changes. We found that Gli2 acts within mouse mammary stromal cells to direct a hormone-responsive niche si...

February 20, 2017

Three new grad students joined the Shin laboratory this spring. Yubin Kim, Sangcheol Lee, and Eunjeong Lee joined the laboratory to pursue their Ph.D. in stem cell / cancer research. We are excited to have them in lab, and WELCOME!!!

November 4, 2016

Our study found that inhibition of Hedgehog pathway intensifies colon inflammation in mice. Inflammatory bowel disease (IBD) is a debilitating disorder with limited treatment options. Genetic augmentation of Hedgehog response and systemic small-molecule Hedgehog pathway activation potently ameliorate colitis and restrain initiation and progression of colitis-induced adenocarcinoma. We thus, in this study, identify stromal cells as cellular coordin...

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Shin Lab | Department of Life Sciences | Pohang University of Science and Technology